Abstract: Bad sea conditions can easily lead to ship collision accidents, in fact, the ship collision process is the coupling of wave load and collision force at sea. According to the nonlinear finite element method, the ship collision model is fully considered, and the data simulation method is used to simulate the ship collision process. The collision results of ships with or without wave action are compared, and the influence of wave incident angle, period and wave height on the damage degree of ship hull side structure is analyzed. The analysis results show that under certain circumstances, the wave action has a great adverse effect on the whole process of ship collision, and the risk avoidance measures are put forward from the point of view of ship engineering.